The celecoxib derivatives AR-12 and AR-14 induce autophagy and clear prion-infected cells from prions
نویسندگان
چکیده
منابع مشابه
THE EXTENDED LAW OF CORRESPONDING - STATES AND THE INTERMOLECULAR POTENTIALS FOR Ar-Ar, Ar-Kr AND Kr-Kr
An inversion procedure is used to obtain from the extended principle of corresponding - states the pair interaction potentials for argon, krypton and its mixture over a tetnperature range from absolute zero to the onset of ionization. The experimentally-reduced viscosity collision integrals obtained from the corresponding - states correlation have been inverted directly to give the reduced...
متن کاملthe extended law of corresponding - states and the intermolecular potentials for ar-ar, ar-kr and kr-kr
an inversion procedure is used to obtain from the extended principle of corresponding - states the pair interaction potentials for argon, krypton and its mixture over a tetnperature range from absolute zero to the onset of ionization. the experimentally-reduced viscosity collision integrals obtained from the corresponding - states correlation have been inverted directly to give the reduced-inte...
متن کاملPrions and prion-like proteins.
Prions are self-replicating protein aggregates and are the primary causative factor in a number of neurological diseases in mammals. The prion protein (PrP) undergoes a conformational transformation leading to aggregation into an infectious cellular pathogen. Prion-like protein spreading and transmission of aggregates between cells have also been demonstrated for other proteins associated with ...
متن کاملa comparative analysis of the marginal microleakages of two pit and fissure sealans, conseal-f and conseal clear
چکیده ندارد.
15 صفحه اولPrions: Portable prion domains
Self-propagating abnormal proteins, prions, have been identified in yeast; asparagine/glutamine-rich 'prion domains' within these proteins can inactivate the linked functional domains; new prion domains and reporters have been used to make 'synthetic prions', leading to discoveries of new natural prions.
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/s41598-017-17770-8